Dwarfism Research Today is a free monthly online journal that collates and summarizes the latest research about Dwarfism, including details on genetics, diet, mental and motor development.

New insights into the combined Cockayne/xeroderma pigmentosum complex: human XPG protein can function in transcription factor stability.

Friedberg EC, Wood RD

Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9072, USA. errol.friedberg@utsouthwestern.edu

A new study provides evidence supporting a function for XPG protein in maintaining the integrity and function of TFIIH (Ito et al. [2007], this issue of Molecular Cell). This observation likely explains some of the clinical features of individuals with both defective DNA repair and development.

Published 30 April 2007 in Mol Cell, 26(2): 162-4.
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